Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 17/20 | 0.60 |
| ▸ | CXCR1 | P25024 | 10/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344796 | 0.91 | CXCR2 (0.65) | CXCR2CXCR1CCR6 | |
| SCHEMBL14639723 | 0.88 | CXCR2 (0.47) | CXCR2CXCR1CCR6 | |
| SCHEMBL14639802 | 0.83 | CXCR2 (0.70) | CXCR2CXCR1 | |
| SCHEMBL12779711 | 0.83 | CXCR2 (0.61) | CXCR2CXCR1CCR6 | |
| SCHEMBL13208178 | 0.81 | CXCR2 (0.69) | CXCR2CXCR1 | |
| SCHEMBL13207149 | 0.81 | CXCR2 (0.63) | CXCR2CXCR1CCR6 | |
| SCHEMBL13345262 | 0.78 | CXCR2 (0.60) | CXCR2CXCR1CCR6 | |
| SCHEMBL13344799 | 0.78 | CXCR2 (0.51) | CXCR2CXCR1CCR6 | |
| SCHEMBL12845106 | 0.78 | CXCR2 (0.73) | CXCR2CXCR1CCR6 | |
| SCHEMBL12845104 | 0.78 | CXCR1 (0.74) | CXCR2CXCR1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005403-A1 | 5,6-DI-SUBSTITUTED OXADIAZOLOPYRAZINES AND THIADIAZOLOPYRAZINES AS CXC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2007-01-11 | — | — | WO | disclosed |