Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.50 |
| ▸ | ALPL | P05186 | 5/20 | 0.50 |
| ▸ | XIAP | P98170 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417594 | 0.84 | TSHR (0.55) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL22215259 | 0.82 | TSHR (0.53) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL19487102 | 0.79 | TSHR (0.54) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL1862337 | 0.79 | TSHR (0.62) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL15911114 | 0.78 | TSHR (0.53) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL3739579 | 0.77 | TSHR (0.60) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4457538 | 0.77 | TSHR (0.60) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13248693 | 0.77 | TSHR (0.51) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9384894 | 0.77 | MEN1 (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13898659 | 0.77 | TSHR (0.47) | TSHRALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007903-A2 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-18 | — | — | WO | disclosed |