SCHEMBL146414

SCHEMBL146414

CCCN(CCC)CCC#N

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.52
TSHR P16473 3/20 0.48
DRD3 P35462 2/20 0.46
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CASP1 P29466 1/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LOX P28300 1/20 0.32
LOXL3 P58215 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
CYP3A4 P08684 1/20 0.32
POLB P06746 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
NLRP3 Q96P20 1/20 0.31
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6858907 1.00 LCK (0.52) LCKTSHRDRD3ALDH1A1TDP1
SCHEMBL15088348 0.97 LCK (0.50) LCKTSHRDRD3ALDH1A1TDP1
SCHEMBL11668634 0.90 LCK (0.56) LCKTSHRDRD3ALDH1A1TDP1
SCHEMBL11687703 0.89 TSHR (0.43) LCKTSHRDRD3ALDH1A1TDP1
SCHEMBL65032 0.87 LCK (0.62) LCKTSHRDRD3ALDH1A1TDP1
SCHEMBL10937095 0.87 LCK (0.58) LCKTSHRDRD3ALDH1A1TDP1
SCHEMBL152635 0.87 LCK (0.58) LCKTSHRDRD3ALDH1A1TDP1
SCHEMBL13844254 0.86 LCK (0.52) LCKTSHRDRD3
SCHEMBL7710167 0.85 LCK (0.56) LCKTSHRDRD3
SCHEMBL714439 0.84 LCK (0.59) LCKTSHRDRD3ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025119782-A1 METHOD FOR THE MANUFACTURE OF NEW AMINE EVONIK OPERATIONS GMBH (DE) 2025-06-12 WO claimed
EP-0001867-A2 Food casing and method of preparing same UNION CARBIDE CORPORATION (US) 1979-05-16 EP claimed
WO-2025119782-A1 METHOD FOR THE MANUFACTURE OF NEW AMINE EVONIK OPERATIONS GMBH (DE) 2025-06-12 WO disclosed
EP-3190208-A1 ELECTROLESS NICKEL PLATING BATHS COMPRISING AMINONITRILES AND A METHOD FOR DEPOSITION OF NICKEL AND NICKEL ALLOYS ATOTECH Deutschland GmbH (DE) 2017-07-12 EP disclosed
EP-2526149-B1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORP (JP) 2017-03-01 EP disclosed
US-9469710-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2016-10-18 US disclosed
US-20150148489-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2015-05-28 US disclosed
US-8735494-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2014-05-27 US disclosed
US-20130085227-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2013-04-04 US disclosed
US-8344066-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2013-01-01 US disclosed
US-20120296041-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-11-22 US disclosed
WO-1999032429-A2 METHOD FOR PRODUCING SECONDARY AMINES FROM NITRILES AND PRIMARY AMINES BASF AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed
EP-0673918-B1 Process for the preparation of peralkylated amines BASF AG (DE) 1999-06-02 EP disclosed
US-5894074-A Preparation of tertiary amines from nitriles and secondary amines BASF AKTIENGESELLSCHAFT (DE) 1999-04-13 US disclosed
EP-0869113-A2 Process for the preparation of tertiary amines fromnitriles and secondary amines BASF AKTIENGESELLSCHAFT (DE) 1998-10-07 EP disclosed
US-5463130-A Preparation of peralkylated amines BASF AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
EP-0673918-A1 Process for the preparation of peralkylated amines BASF AKTIENGESELLSCHAFT (DE) 1995-09-27 EP disclosed
US-4064164-A SEQUESTERING AGENTS, ANTICARIES AGENTS, CALCIUM OR PHOSPHATE METABOLISM ABNORMALITIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) 1977-12-20 US disclosed
US-4052363-A BETA-AMINO PROPIONITRILE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-10-04 US disclosed
US-4038210-A BETA-AMINO NITRILE CATALYSTS FOR POLYURETHANE PREPARATION UNION CARBIDE CORPORATION (US) 1977-07-26 US disclosed