Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14643010 | 0.88 | MAPK8 (0.78) | MAPK8MAPK9 | |
| SCHEMBL14643009 | 0.88 | MAPK8 (0.68) | MAPK8MAPK9 | |
| SCHEMBL14617180 | 0.87 | MAPK8 (0.72) | MAPK8MAPK9 | |
| SCHEMBL14575606 | 0.87 | MAPK8 (0.72) | MAPK8MAPK9 | |
| Hydrochloric Acid SCHEMBL14576577 | 0.86 | MAPK8 (0.71) | MAPK8MAPK9 | |
| SCHEMBL14575850 | 0.86 | MAPK8 (1.00) | MAPK8 | |
| SCHEMBL14575822 | 0.85 | MAPK8 (1.00) | MAPK8 | |
| SCHEMBL15164771 | 0.84 | MAPK8 (0.68) | MAPK8MAPK9 | |
| SCHEMBL14575546 | 0.84 | MAPK8 (1.00) | MAPK8 | |
| SCHEMBL14575311 | 0.83 | MAPK8 (1.00) | MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501732-B2 | Aminomethyl quinolone compounds | HOFFMANN-LA ROCHE INC. (US) | 2013-08-06 | — | — | US | disclosed |
| WO-2013007676-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | WO | disclosed |
| US-20130018043-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | BILOTTA JOSEPH A (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018043-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | MAP3K1, MAP3K11, MAP3K5 | MAPK8 31/4885MAPK9 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.