SCHEMBL14643199

SCHEMBL14643199

COc1ccc(N(c2ccc(C=C3C(=O)c4cc5ccccc5cc4C3=O)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
KMT2A Q03164 4/20 0.54
USP2 O75604 1/20 0.54
PKM P14618 1/20 0.54
LCK P06239 2/20 0.49
GAPDH P04406 1/20 0.46
PRKACA P17612 1/20 0.45
PRKACG P22612 1/20 0.45
PRKACB P22694 1/20 0.45
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 2/20 0.45
ACHE P22303 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALPL P05186 1/20 0.45
ALPI P09923 1/20 0.45
ALPG P10696 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
APP P05067 1/20 0.45
SNCA P37840 1/20 0.45
CRHBP P24387 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14617503 0.95 MAPT (0.49) MAPTKMT2AUSP2PKMLCK
SCHEMBL14706649 0.92 MAPT (0.49) MAPTKMT2AUSP2PKMLCK
SCHEMBL17774100 0.88 MAPT (0.45) MAPTKMT2AUSP2PKMLCK
SCHEMBL2606262 0.87 MAPT (0.47) MAPTKMT2AUSP2PKMLCK
SCHEMBL2606263 0.86 CSNK2A2 (0.50) MAPTKMT2AUSP2PKMLCK
SCHEMBL12776357 0.86 KMT2A (0.57) MAPTKMT2AUSP2PKMLCK
SCHEMBL10086935 0.85 MAPT (0.45) MAPTKMT2AUSP2PKMLCK
SCHEMBL10134207 0.85 MAPT (0.43) MAPTKMT2AUSP2PKMLCK
SCHEMBL10086940 0.84 CSNK2A2 (0.51) MAPTKMT2AUSP2PKMLCK
SCHEMBL10134214 0.83 MAPT (0.44) MAPTKMT2AUSP2PKMLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809847-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-08-19 US disclosed
US-20130015435-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-17 US disclosed