Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 18/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730671 | 0.81 | PRMT5 (0.51) | PRMT5WDR77ADK | |
| SCHEMBL731192 | 0.81 | PRMT5 (0.51) | PRMT5WDR77ADK | |
| SCHEMBL873740 | 0.81 | PRMT5 (0.51) | PRMT5WDR77ADK | |
| SCHEMBL4343111 | 0.81 | PRMT5 (0.51) | PRMT5WDR77ADK | |
| SCHEMBL14640072 | 0.81 | PRMT5 (0.51) | PRMT5WDR77ADK | |
| SCHEMBL15962811 | 0.79 | PRMT5 (0.53) | PRMT5WDR77ADK | |
| SCHEMBL15960626 | 0.79 | PRMT5 (0.53) | PRMT5WDR77ADK | |
| SCHEMBL14643351 | 0.76 | PRMT5 (0.50) | PRMT5WDR77ADK | |
| SCHEMBL15960628 | 0.75 | PRMT5 (0.47) | PRMT5WDR77ADK | |
| SCHEMBL15960615 | 0.74 | PRMT5 (0.48) | PRMT5WDR77ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013009735-A1 | 5'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | WO | disclosed |