Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 10/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656424 | 1.00 | BTN3A1 (0.54) | BTN3A1LMNAMAPK1HPGDKMT2A | |
| SCHEMBL20959996 | 1.00 | BTN3A1 (0.54) | BTN3A1LMNAMAPK1HPGDKMT2A | |
| SCHEMBL15507071 | 1.00 | BTN3A1 (0.54) | BTN3A1LMNAMAPK1HPGDKMT2A | |
| SCHEMBL12378076 | 0.88 | BTN3A1 (0.56) | BTN3A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL19778357 | 0.88 | BTN3A1 (0.56) | BTN3A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL18067176 | 0.88 | BTN3A1 (0.56) | BTN3A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL15682968 | 0.88 | BTN3A1 (0.56) | BTN3A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL15685881 | 0.88 | BTN3A1 (0.56) | BTN3A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL12214044 | 0.88 | BTN3A1 (0.56) | BTN3A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL18512732 | 0.88 | BTN3A1 (0.56) | BTN3A1LMNAHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013009737-A1 | 5'-SUBSTITUTED NUCLEOSIDE ANALOGS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | WO | disclosed |