Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21041793 | 1.00 | KDM4E (0.60) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL18588225 | 0.86 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14930734 | 0.86 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL24899909 | 0.84 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL18289820 | 0.84 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL16627562 | 0.84 | KDM4E (0.40) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL4762422 | 0.83 | KDM4E (0.65) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL16593142 | 0.82 | MEN1 (0.63) | KDM4EMAPK1HIF1APAOXALDH1A1 | |
| SCHEMBL24899917 | 0.82 | KDM4E (0.59) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL12153331 | 0.82 | CA1 (0.48) | ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8907053-B2 | Immunosuppression modulating compounds | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |
| US-8357375-B2 | Process for the preparation and use of a bivalent vaccine against morphine-heroine addiction | INSTITUTO NACIONAL DE PSIQUIATRIA RAMON DE LA FUENTE MUNIZ (MX) | 2013-01-22 | — | — | US | disclosed |
| US-20110318373-A1 | IMMUNOSUPPRESSION MODULATING COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110318373-A1 | IMMUNOSUPPRESSION MODULATING COMPOUNDS | CD274, PDCD1, PDCD1LG2 | KDM4E 2955/4885MAPK1 74/4885HIF1A 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.