SCHEMBL14645299

SCHEMBL14645299

COc1ccccc1NCc1ccccc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.68
CA12 O43570 1/20 0.68
CA9 Q16790 1/20 0.68
MAPT P10636 10/20 0.61
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
ALDH1A1 P00352 6/20 0.61
HTT P42858 2/20 0.61
MPO P05164 2/20 0.59
GAA P10253 5/20 0.58
L3MBTL1 Q9Y468 4/20 0.58
TP53 P04637 2/20 0.58
MAPK1 P28482 2/20 0.58
HSD17B10 Q99714 1/20 0.58
KDM4E B2RXH2 5/20 0.55
LMNA P02545 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
HPGD P15428 2/20 0.52
TSHR P16473 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7115595 0.83 TP53 (0.50) CA2CA12CA9MAPTMEN1
SCHEMBL27930738 0.83 GAA (0.58) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL7157974 0.82 GAA (0.53) CA2CA12CA9MAPTMEN1
SCHEMBL6069558 0.82 CA12 (0.53) CA2CA12CA9MAPTMEN1
SCHEMBL14773903 0.81 MAPT (0.68) CA2CA12CA9MAPTMEN1
SCHEMBL14821593 0.81 CA12 (0.64) CA2CA12CA9MAPTMEN1
SCHEMBL10782516 0.80 CA12 (0.88) CA2CA12CA9MAPTMEN1
SCHEMBL6410863 0.78 CA12 (0.84) CA2CA12CA9MAPTMEN1
SCHEMBL12808226 0.77 CA12 (0.75) CA2CA12CA9MAPTMEN1
SCHEMBL6353730 0.77 MAPT (0.96) CA2CA12CA9MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103781823-B Containing titanium complex and condensation catalyst, prepare the method for this catalyst and comprise the compositions of this catalyst 道康宁公司 2016-08-17 CN disclosed
US-9371422-B2 Titanium containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-06-21 US disclosed
US-9371422-B2 Titanium containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-06-21 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-20150210809-A1 Samarium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW CORNING CORPORATION 2015-07-30 US disclosed
US-20150210809-A1 Samarium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW CORNING CORPORATION 2015-07-30 US disclosed
US-20150210809-A1 Samarium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW CORNING CORPORATION 2015-07-30 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-20140213690-A1 Titanium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW CORNING CORPORATION (US) 2014-07-31 US disclosed
EP-2731716-A1 SAMARIUM CONTAINING COMPLEXES AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS Dow Corning Corporation (US) 2014-05-21 EP disclosed
CN-103242367-A 2-aryloxy-3-aryl-3,4-dihydro-2H-1,3,2-benzo-phosphoramidate compound with insecticidal activity and applications thereof UNIV HUNAN SCI & TECHNOLOGY 2013-08-14 CN disclosed
CN-103193823-A Novel 3,4-dihydro-2H-1,3,2-benzooxazaphosphorinane compounds with bactericidal activity and insecticidal activity and application thereof HUNAN RES INST CHEMICAL IND 2013-07-10 CN disclosed
WO-2013052585-A2 IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-04-11 WO disclosed
WO-2013036546-A2 TITANIUM CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-14 WO disclosed
WO-2013009836-A1 SAMARIUM CONTAINING COMPLEXES AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-01-17 WO disclosed
WO-2013009836-A1 SAMARIUM CONTAINING COMPLEXES AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-01-17 WO disclosed
CN-1926081-B Metal complexes for use in olefin methathesis and atom or group transfer reactions UNIV GENT 2011-06-15 CN disclosed
CN-1926081-A Metal complexes for use in olefin methathesis and atom or group transfer reactions UNIV GENT (BE) 2007-03-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210809-A1 Samarium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts SMARCC2, SMARCC1, RAD51 CA2 3730/4885CA12 3092/4885CA9 2217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.