SCHEMBL14645346

SCHEMBL14645346

CCCCCCCCCCN(C)CCOP(=O)(O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.63
LPAR1 Q92633 6/20 0.63
LPAR2 Q9HBW0 4/20 0.63
S1PR2 O95136 1/20 0.61
S1PR1 P21453 1/20 0.61
S1PR3 Q99500 1/20 0.61
S1PR5 Q9H228 1/20 0.61
GGPS1 O95749 4/20 0.53
FDPS P14324 1/20 0.51
AGTR1 P30556 1/20 0.51
OPRM1 P35372 1/20 0.51
PDE3A Q14432 1/20 0.51
LPAR5 Q9H1C0 2/20 0.45
LPAR6 P43657 1/20 0.42
LPAR4 Q99677 1/20 0.42
ENPP2 Q13822 1/20 0.42
MVD P53602 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14878491 1.00 LPAR3 (0.63) LPAR3LPAR1LPAR2S1PR2S1PR1
SCHEMBL9814344 0.98 LPAR3 (0.61) LPAR3LPAR1LPAR2S1PR2S1PR1
SCHEMBL15780701 0.93 LPAR3 (0.57) LPAR3LPAR1LPAR2S1PR2S1PR1
SCHEMBL15780662 0.85 LPAR3 (0.50) LPAR3LPAR1LPAR2S1PR2S1PR1
SCHEMBL9814347 0.85 S1PR2 (0.56) LPAR3LPAR1LPAR2S1PR2S1PR1
SCHEMBL28355690 0.84 LPAR3 (0.66) LPAR3LPAR1LPAR2S1PR2S1PR1
SCHEMBL26624051 0.84 LPAR3 (0.66) LPAR3LPAR1LPAR2S1PR2S1PR1
Phosphoric Acid SCHEMBL29166689 0.82 S1PR2 (0.77) LPAR3LPAR1LPAR2S1PR2S1PR1
Phosphoric Acid SCHEMBL31190165 0.82 S1PR2 (0.77) LPAR3LPAR1LPAR2S1PR2S1PR1
Phosphoric Acid SCHEMBL19812153 0.82 S1PR2 (0.77) LPAR3LPAR1LPAR2S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9513253-B2 Droplet actuators and techniques for droplet-based enzymatic assays ADVANCED LIQUID LOGIC, INC. (US) 2016-12-06 US claimed
US-20140246319-A1 DROPLET ACTUATORS AND TECHNIQUES FOR DROPLET-BASED ASSAYS ADVANCED LIQUID LOGIC, INC. (US) 2014-09-04 US claimed
WO-2013009927-A2 DROPLET ACTUATORS AND TECHNIQUES FOR DROPLET-BASED ASSAYS ADVANCED LIQUID LOGIC, INC. (US) 2013-01-17 WO claimed
US-9513253-B2 Droplet actuators and techniques for droplet-based enzymatic assays ADVANCED LIQUID LOGIC, INC. (US) 2016-12-06 US disclosed
US-20140246319-A1 DROPLET ACTUATORS AND TECHNIQUES FOR DROPLET-BASED ASSAYS ADVANCED LIQUID LOGIC, INC. (US) 2014-09-04 US disclosed
WO-2013009927-A2 DROPLET ACTUATORS AND TECHNIQUES FOR DROPLET-BASED ASSAYS ADVANCED LIQUID LOGIC, INC. (US) 2013-01-17 WO disclosed