⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012737 | 0.71 | — | — | |
| SCHEMBL3376292 | 0.59 | — | — | |
| SCHEMBL23829559 | 0.55 | — | — | |
| SCHEMBL1292309 | 0.55 | — | — | |
| SCHEMBL935173 | 0.55 | — | — | |
| SCHEMBL1402453 | 0.55 | — | — | |
| SCHEMBL1576988 | 0.55 | — | — | |
| SCHEMBL19712058 | 0.55 | — | — | |
| SCHEMBL11930612 | 0.55 | — | — | |
| SCHEMBL11408850 | 0.53 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729458-B1 | PROCESSES FOR THE PREPARATION OF THIETANAMINE | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-05 | — | — | EP | disclosed |
| CN-105837553-A | PROCESSES FOR THE PREPARATION OF THIETANAMINE | 先正达参股股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-103649070-B | Process for the preparation of thietanamine | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-18 | — | — | CN | disclosed |
| US-9006456-B2 | Processes for the preparation of thietanamine | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-14 | — | — | US | disclosed |
| US-20140187788-A1 | PROCESSES FOR THE PREPARATION OF THIETANAMINE | SYNGENTA PARTICIPATIONS AG (CH) | 2014-07-03 | — | — | US | disclosed |
| EP-2729458-A2 | PROCESSES FOR THE PREPARATION OF THIETANAMINE | Syngenta Participations AG (CH) | 2014-05-14 | — | — | EP | disclosed |
| CN-103649070-A | Process for the preparation of thietanamine | SYNGENTA PARTICIPATIONS AG | 2014-03-19 | — | — | CN | disclosed |
| WO-2013007582-A2 | PROCESSES FOR THE PREPARATION OF THIETANAMINE | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-17 | — | — | WO | disclosed |