Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.84 |
| ▸ | GAA | P10253 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NAMPT | P43490 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688685 | 1.00 | HPGD (0.84) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL1102309 | 1.00 | HPGD (0.84) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL12812547 | 0.95 | HPGD (0.75) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL10720276 | 0.91 | GAA (1.00) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL13753546 | 0.89 | HPGD (0.71) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL10723873 | 0.89 | HPGD (0.76) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL19454030 | 0.88 | HPGD (0.64) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL10722429 | 0.85 | MEN1 (0.70) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL16254905 | 0.84 | GAA (0.84) | HPGDGAAMEN1KMT2AMAPK1 | |
| SCHEMBL16254982 | 0.84 | HPGD (0.84) | HPGDGAAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013007371-A2 | KINETIC RESOLUTION OF CHIRAL AMINES | ETH ZURICH (CH) | 2013-01-17 | — | — | WO | disclosed |
| WO-2013007371-A2 | KINETIC RESOLUTION OF CHIRAL AMINES | ETH ZURICH (CH) | 2013-01-17 | — | — | WO | disclosed |