⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071086 | 0.85 | — | — | |
| SCHEMBL19852660 | 0.80 | — | — | |
| SCHEMBL13618586 | 0.78 | — | — | |
| SCHEMBL14734425 | 0.77 | — | — | |
| SCHEMBL12288556 | 0.74 | — | — | |
| SCHEMBL13456825 | 0.74 | — | — | |
| SCHEMBL14724756 | 0.74 | — | — | |
| SCHEMBL10453987 | 0.73 | — | — | |
| SCHEMBL16359271 | 0.73 | — | — | |
| SCHEMBL21137246 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773869-B9 | MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR | TRANZYME PHARMA INC (CA) | 2013-01-23 | — | — | EP | disclosed |