SCHEMBL14647114

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647240	0.82	PARP1 (0.44)	PARP1GRIK1GRIA1SPRMEN1
	SCHEMBL14647144	0.75	GRIK1 (0.34)	PARP1GRIK1GRIA1MEN1ALDH1A1
	SCHEMBL14647112	0.74	PARP1 (0.46)	CSNK2A1CSNK2A2CSNK2BPARP1KDM4E
	SCHEMBL14647113	0.71	HDAC1 (0.42)	PARP1ALDH1A1KDM4EFEN1DAO
	SCHEMBL14647133	0.70	PARP1 (0.40)	PARP1GRIK1GRIA1ALDH1A1
	SCHEMBL31257810	0.64	GRIK1 (0.55)	GRIK1GRIA1MEN1ALDH1A1MAPT
	SCHEMBL30698069	0.63	POLB (0.39)	PARP1GRIK1GRIA1MEN1ALDH1A1
	SCHEMBL31751011	0.61	GRIK1 (0.48)	PARP1GRIK1GRIA1SPRMEN1
	SCHEMBL18689573	0.61	GRIK1 (0.48)	GRIK1GRIA1MEN1ALDH1A1MAPT
	SCHEMBL1451202	0.60	CSNK2A1 (1.00)	CSNK2A1CSNK2A2CSNK2BPARP1SPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.