Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670590 | 0.92 | CNR2 (0.35) | CNR2 | |
| SCHEMBL1621233 | 0.83 | CNR2 (0.31) | CNR2 | |
| SCHEMBL766694 | 0.82 | CNR2 (0.46) | CNR2 | |
| SCHEMBL1621074 | 0.82 | EPHX1 (0.32) | CNR2MMP13EPHX2 | |
| SCHEMBL10171735 | 0.79 | CNR2 (0.32) | CNR2 | |
| SCHEMBL766807 | 0.79 | CNR2 (0.32) | CNR2 | |
| SCHEMBL2184860 | 0.79 | CNR2 (0.32) | CNR2 | |
| SCHEMBL1691293 | 0.74 | TP53 (0.45) | — | |
| SCHEMBL14664306 | 0.69 | CNR2 (0.32) | CNR2 | |
| SCHEMBL20594856 | 0.66 | EPHX2 (0.33) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342200-B1 | Compounds which selectively modulate the cb2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2013-01-23 | — | — | EP | disclosed |