Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | AOC2 | O75106 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147821 | 0.88 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL13392940 | 0.84 | CNR2 (0.32) | CNR2CNR1AOC2MAOAJAK2 | |
| SCHEMBL13448691 | 0.84 | CNR2 (0.32) | CNR2CNR1AOC2MAOAJAK2 | |
| SCHEMBL10171246 | 0.82 | CNR2 (0.34) | CNR2CNR1AOC2MAOAJAK2 | |
| SCHEMBL10171252 | 0.82 | CNR2 (0.34) | CNR2CNR1AOC2MAOAJAK2 | |
| SCHEMBL13392854 | 0.81 | — | — | |
| SCHEMBL13391412 | 0.81 | — | — | |
| SCHEMBL10171815 | 0.81 | CNR2 (0.40) | CNR2CNR1AOC2MAOA | |
| SCHEMBL10171801 | 0.81 | CNR2 (0.40) | CNR2CNR1AOC2MAOA | |
| SCHEMBL13392840 | 0.80 | CNR2 (0.40) | CNR2CNR1AOC2MAOAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342200-B1 | Compounds which selectively modulate the cb2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2013-01-23 | — | — | EP | disclosed |