Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.35 |
| ▸ | GRM8 | O00222 | 3/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744927 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1GRM4GRM8 | |
| SCHEMBL3238992 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1GRM4GRM8 | |
| SCHEMBL13757663 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1GRM4GRM8 | |
| SCHEMBL2487735 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1GRM4GRM8 | |
| SCHEMBL10272013 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1GRM4GRM8 | |
| SCHEMBL16575073 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1GRM4GRM8 | |
| Hydrochloric Acid SCHEMBL3238987 | 0.98 | GRM2 (0.37) | GRM2GRM5GRM1GRM4GRM8 | |
| Hydrochloric Acid SCHEMBL32674363 | 0.98 | GRM2 (0.37) | GRM2GRM5GRM1GRM4GRM8 | |
| Hydrochloric Acid SCHEMBL2487732 | 0.98 | GRM2 (0.37) | GRM2GRM5GRM1GRM4GRM8 | |
| Hydrochloric Acid SCHEMBL2744924 | 0.98 | GRM2 (0.37) | GRM2GRM5GRM1GRM4GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2028186-B1 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM CA LTD (CA) | 2013-01-23 | — | — | EP | disclosed |