SCHEMBL14650433

SCHEMBL14650433

Cc1cc(N(c2ccc(C=Cc3ccc(N(c4ccc(COC5CCCCO5)cc4)c4ccc(COC5CCCCO5)c(C)c4)cc3)cc2)c2ccc(COC3CCCCO3)cc2)ccc1COC1CCCCO1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ICAM1 P05362 1/20 0.35
SELE P16581 1/20 0.35
CREBBP Q92793 2/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
EP300 Q09472 1/20 0.32
KDM4C Q9H3R0 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MGLL Q99685 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14650434 0.96 NPC1 (0.35) CREBBPNPC1RAB9AEP300KDM4C
SCHEMBL14650389 0.94 ICAM1 (0.38) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL14650388 0.94 ICAM1 (0.38) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL14650385 0.90 ICAM1 (0.36) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL14650403 0.90 ICAM1 (0.36) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL14650425 0.90 ICAM1 (0.36) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL15831452 0.89 ICAM1 (0.38) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL14650432 0.89 ICAM1 (0.38) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL14650409 0.88 ICAM1 (0.42) ICAM1SELECREBBPNPC1RAB9A
SCHEMBL14650413 0.88 KDM4C (0.36) ICAM1SELECREBBPNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9201319-B2 Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-12-01 US disclosed
US-9201319-B2 Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-12-01 US disclosed
US-20140178810-A1 IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-06-26 US disclosed
US-20140178810-A1 IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-06-26 US disclosed
US-8679712-B2 Photoreceptor and image forming method, image forming apparatus, and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2014-03-25 US disclosed
US-8679712-B2 Photoreceptor and image forming method, image forming apparatus, and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2014-03-25 US disclosed
US-20130295497-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-11-07 US disclosed
US-20130295497-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-11-07 US disclosed
US-20130022903-A1 PHOTORECEPTOR AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20130022903-A1 PHOTORECEPTOR AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed