Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650527 | 0.95 | CYP1B1 (0.40) | CYP1B1TDP1L3MBTL1RAB9ASTAT3 | |
| SCHEMBL14650517 | 0.90 | STAT3 (0.42) | RAB9ASTAT3HIF1AALDH1A1MEN1 | |
| SCHEMBL14650509 | 0.90 | STAT3 (0.42) | RAB9ASTAT3HIF1AALDH1A1MEN1 | |
| SCHEMBL14650522 | 0.89 | MEN1 (0.38) | CYP1B1TDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL14650548 | 0.88 | STAT3 (0.41) | TDP1L3MBTL1RAB9ASTAT3HIF1A | |
| SCHEMBL14650543 | 0.88 | STAT3 (0.41) | TDP1L3MBTL1RAB9ASTAT3HIF1A | |
| SCHEMBL14650516 | 0.87 | STAT3 (0.40) | TDP1L3MBTL1RAB9ASTAT3HIF1A | |
| SCHEMBL14650520 | 0.87 | STAT3 (0.40) | TDP1L3MBTL1RAB9ASTAT3HIF1A | |
| SCHEMBL14650529 | 0.87 | STAT3 (0.40) | TDP1L3MBTL1RAB9ASTAT3HIF1A | |
| SCHEMBL14650537 | 0.87 | STAT3 (0.40) | TDP1L3MBTL1RAB9ASTAT3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |