Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 7/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268812 | 0.84 | ESR1 (0.50) | STAT3HIF1ATERTMEN1NPC1 | |
| SCHEMBL14650632 | 0.76 | ESR1 (0.37) | STAT3HIF1ATERTMEN1ALDH1A1 | |
| SCHEMBL14650619 | 0.76 | STAT3 (0.50) | STAT3HIF1ATERTTOP2AKDM4E | |
| SCHEMBL14650624 | 0.75 | STAT3 (0.58) | STAT3HIF1ATERTTOP2AKDM4E | |
| SCHEMBL14650580 | 0.75 | STAT3 (0.58) | STAT3HIF1ATERTTOP2AKDM4E | |
| SCHEMBL10003923 | 0.75 | STAT3 (0.58) | STAT3HIF1ATERTTOP2AKDM4E | |
| SCHEMBL11923437 | 0.73 | STAT3 (0.56) | STAT3HIF1ATERTTOP2AKDM4E | |
| SCHEMBL10004510 | 0.73 | STAT3 (0.56) | STAT3HIF1ATERTTOP2AKDM4E | |
| SCHEMBL11923436 | 0.73 | STAT3 (0.56) | STAT3HIF1ATERTTOP2AKDM4E | |
| SCHEMBL11923433 | 0.72 | STAT3 (0.55) | STAT3HIF1ATERTTOP2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |