⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258596 | 0.77 | — | — | |
| SCHEMBL8262022 | 0.73 | SETD7 (0.31) | — | |
| SCHEMBL14652790 | 0.73 | — | — | |
| SCHEMBL12443533 | 0.67 | — | — | |
| SCHEMBL14652751 | 0.64 | — | — | |
| SCHEMBL14652656 | 0.64 | — | — | |
| SCHEMBL15430552 | 0.64 | — | — | |
| SCHEMBL12976024 | 0.61 | — | — | |
| SCHEMBL20345796 | 0.56 | — | — | |
| SCHEMBL18830814 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081636-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2020-04-23 | — | — | WO | disclosed |
| WO-2013012298-A1 | 9H-CARBAZOLE COMPOUNDS AND ELECTROLUMINESCENT DEVICES INVOLVING THEM | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2013-01-24 | — | — | WO | disclosed |