Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | BCL2L1 | Q07817 | 17/20 | 0.58 |
| ▸ | BCL2 | P10415 | 13/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 11/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1955748 | 0.91 | BCL2L1 (0.59) | MAPTBCL2L1BCL2MCL1MAPK1 | |
| SCHEMBL30112869 | 0.91 | BCL2L1 (0.58) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 | |
| SCHEMBL30112781 | 0.90 | BCL2L1 (0.57) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 | |
| SCHEMBL29588272 | 0.90 | BCL2L1 (0.57) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 | |
| SCHEMBL30112824 | 0.89 | BCL2L1 (0.56) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 | |
| SCHEMBL30622006 | 0.89 | BCL2L1 (0.54) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 | |
| SCHEMBL29644474 | 0.89 | BCL2L1 (0.54) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 | |
| SCHEMBL30112778 | 0.89 | BCL2L1 (0.55) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 | |
| SCHEMBL29588211 | 0.89 | BCL2L1 (0.55) | MAPTBCL2L1BCL2MCL1MAPK1 | |
| SCHEMBL2951985 | 0.88 | BCL2L1 (0.62) | MAPTALDH1A1HTTSMN1; SMN2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550258-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbvie Inc. (US) | 2013-01-30 | — | — | EP | disclosed |