Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1347032 | 0.94 | NQO2 (0.42) | NQO2MTNR1AMTNR1BCYP19A1CYP26A1 | |
| SCHEMBL1346063 | 0.94 | NQO2 (0.48) | NQO2MTNR1AMTNR1BCYP19A1KDM1A | |
| SCHEMBL1344502 | 0.86 | NQO2 (0.43) | NQO2MTNR1AMTNR1BOPRM1OPRD1 | |
| SCHEMBL12133256 | 0.86 | NQO2 (0.43) | NQO2MTNR1AMTNR1BCYP19A1CYP26A1 | |
| SCHEMBL1344331 | 0.83 | NQO2 (0.44) | NQO2MTNR1AMTNR1BOPRM1OPRD1 | |
| SCHEMBL1346637 | 0.83 | NQO2 (0.46) | NQO2MTNR1AMTNR1BOPRM1KDM1A | |
| SCHEMBL1346589 | 0.83 | NQO2 (0.43) | NQO2MTNR1AMTNR1BOPRM1KDM1A | |
| SCHEMBL1344496 | 0.82 | NQO2 (0.41) | NQO2MTNR1AMTNR1BOPRM1OPRD1 | |
| SCHEMBL12133264 | 0.81 | NQO2 (0.42) | NQO2MTNR1AMTNR1BCYP19A1CYP26A1 | |
| SCHEMBL1346374 | 0.81 | NQO2 (0.48) | NQO2MTNR1AMTNR1BCYP19A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406206-B1 | TETRAHYDRONAPHTHALEN-2-OL DERIVATIVES | MSD OSS BV (NL) | 2013-01-30 | — | — | EP | disclosed |