⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700812 | 0.69 | — | — | |
| SCHEMBL627363 | 0.67 | — | — | |
| SCHEMBL33042 | 0.67 | — | — | |
| SCHEMBL251464 | 0.62 | — | — | |
| SCHEMBL14616085 | 0.61 | — | — | |
| SCHEMBL16096520 | 0.61 | — | — | |
| SCHEMBL30501 | 0.61 | — | — | |
| SCHEMBL1647699 | 0.61 | — | — | |
| SCHEMBL28949060 | 0.61 | — | — | |
| SCHEMBL29000075 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736918-B1 | PROGESTERONE ANTAGONISTS | EVESTRA INC (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-2999475-B1 | IMIDAZOLYL PROGESTERONE ANTAGONISTS | EVESTRA INC (US) | 2018-07-25 | — | — | EP | disclosed |
| US-20180155386-A1 | PROGESTERONE ANTAGONISTS | EVESTRA, INC. | 2018-06-07 | — | — | US | disclosed |
| EP-2999475-A2 | IMIDAZOLYL PROGESTERONE ANTAGONISTS | Evestra, Inc. (US) | 2016-03-30 | — | — | EP | disclosed |
| US-9096641-B2 | Imidazolyl progesterone antagonists | EVESTRA, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140364600-A1 | IMIDAZOLYL PROGESTERONE ANTAGONISTS | EVESTRA, INC. | 2014-12-11 | — | — | US | disclosed |
| WO-2014197653-A2 | IMIDAZOLYL PROGESTERONE ANTAGONISTS | EVESTRA, INC. (US) | 2014-12-11 | — | — | WO | disclosed |
| EP-2736918-A1 | PROGESTERONE ANTAGONISTS | Evestra, Inc. (US) | 2014-06-04 | — | — | EP | disclosed |
| US-20130029953-A1 | PROGESTERONE ANTAGONISTS | EVESTRA, INC. | 2013-01-31 | — | — | US | disclosed |
| WO-2013016725-A1 | PROGESTERONE ANTAGONISTS | EVESTRA, INC. (US) | 2013-01-31 | — | — | WO | disclosed |