Diphenylmethane

Diphenylmethane

SCHEMBL14656232

Cc1c(N=C=O)cccc1N=C=O.N=C=O.N=C=O.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.65
TSHR P16473 1/20 0.42
CALM1 P0DP23 1/20 0.39
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
LMNA P02545 1/20 0.35
TRPA1 O75762 1/20 0.34
LTA4H P09960 1/20 0.33
CYP1A2 P05177 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
MAPT P10636 2/20 0.32
PLA2G10 O15496 1/20 0.32
PLA2G2A P14555 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28583292 0.86 CYP3A4 (0.87) CYP3A4TSHRGABRA1GABRB2TRPA1
Toluene SCHEMBL28941697 0.85 CYP3A4 (0.71) CYP3A4TSHRGABRA1GABRB2LMNA
Naphthalene SCHEMBL28560718 0.83 CYP3A4 (0.74) CYP3A4GABRA1GABRB2TRPA1CYP1A2
SCHEMBL10873731 0.82 CYP3A4 (0.67) CYP3A4TSHRGABRA1GABRB2TRPA1
SCHEMBL15092 0.80 CYP3A4 (1.00) CYP3A4TSHRGABRA1GABRB2TRPA1
Toluene SCHEMBL28871050 0.79 CYP3A4 (0.80) CYP3A4TSHRGABRA1GABRB2LMNA
Diphenylmethane SCHEMBL8396621 0.79 CYP3A4 (0.42) CYP3A4TSHRCALM1LMNATRPA1
Methane SCHEMBL17504404 0.79 CYP3A4 (0.39) CYP3A4TSHRCALM1GABRA1GABRB2
SCHEMBL27946613 0.78 CYP3A4 (0.95) CYP3A4TSHRGABRA1GABRB2TRPA1
Toluene Diisocyanate SCHEMBL3468300 0.78 CYP3A4 (0.67) CYP3A4TSHRCALM1LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130030145-A1 BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2013-01-31 US disclosed