SCHEMBL146602

SCHEMBL146602

Oc1ncc(Br)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2114543 0.97
SCHEMBL20696081 0.97
SCHEMBL1080070 0.72
SCHEMBL198651 0.72
SCHEMBL16668494 0.69 SMN1; SMN2 (0.39)
SCHEMBL1644424 0.67
SCHEMBL236034 0.67
SCHEMBL15266120 0.67 KDM4E (0.38)
SCHEMBL117561 0.67
SCHEMBL1422023 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644594-B Preparation method of 5-bromo-2-chloropyrimidine 郑州猫眼农业科技有限公司 2024-06-11 CN claimed
CN-117343273-A Self-healing antibacterial polyurethane elastomer and preparation method thereof 江南大学 2024-01-05 CN claimed
CN-113683571-B Preparation method of 2-methyl-5-bromopyrimidine 上海日异生物科技有限公司 2023-02-28 CN claimed
CN-115193403-A Metal-organic framework material capable of enriching water in dry air, preparation and application thereof 南开大学 2022-10-18 CN claimed
CN-114644594-A Preparation method of 5-bromo-2-chloropyrimidine 郑州猫眼农业科技有限公司 2022-06-21 CN claimed
CN-113683571-A Preparation method of 2-methyl-5-bromopyrimidine 上海日异生物科技有限公司 2021-11-23 CN claimed
EP-0522964-B1 Compositions to arrest hair loss and to induce and stimulate hair growth based on 2,4-diamino-pyrimidin-3-oxide derivatives OREAL (FR) 2000-10-04 EP claimed
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12612396-B1 Modulators of beta catenin and uses thereof DEWPOINT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-12559486-B2 Tau-protein targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
US-12528827-B2 Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-20 US disclosed
US-12410179-B2 Modulators of TNF alpha activity and uses thereof RAYTHERA, INC. (US) 2025-09-09 US disclosed
EP-4605089-A1 COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K Mekanistic Therapeutics LLC (US) 2025-08-27 EP disclosed
US-4772702-A Preparation of (thiono)phosphoric esters BAYER AKTIENGESELLSCHAFT (DE) 1988-09-20 US disclosed
US-4753930-A Insecticidal and nematicidal pyrimidinyl-thionophosphoric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1988-06-28 US disclosed
EP-0168704-B1 THIONOPHOSPHORIC-ACID ESTERS OF PYRIMIDINYL BAYER AG (DE) 1988-06-22 EP disclosed
EP-0207412-A2 Process for preparing esters of (thiono)phosphoric acid BAYER AG (DE) 1987-01-07 EP disclosed
EP-0168704-A1 Thionophosphoric-acid esters of pyrimidinyl BAYER AG (DE) 1986-01-22 EP disclosed
US-4093718-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DT) 1978-06-06 US disclosed
US-4014996-A INSECTICIDES, ACARICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed