Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.65 |
| ▸ | HMGCR | P04035 | 3/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.65 |
| ▸ | PDE6D | O43924 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15726406 | 0.93 | SLCO1B1 (0.75) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL17704836 | 0.84 | SLCO1B1 (0.82) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL14669559 | 0.84 | SLCO1B1 (0.60) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL17704920 | 0.84 | SLCO1B1 (0.81) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL13316782 | 0.82 | SLCO1B1 (0.83) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL12464026 | 0.82 | SLCO1B1 (0.83) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL12507372 | 0.82 | SLCO1B1 (0.82) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL10024049 | 0.82 | SLCO1B1 (0.82) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL14414154 | 0.81 | SLCO1B1 (0.79) | SLCO1B1HMGCRABCB1ABCC2PDE6D | |
| SCHEMBL17704842 | 0.81 | SLCO1B1 (0.81) | SLCO1B1HMGCRABCB1ABCC2PDE6D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013016696-A1 | ANTIOXIDANT, NEUROPROTECTIVE AND ANTINEOPLASTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT ON AN AMPHIPHILIC SPACER OR AN AMPHIPHILIC POLYMER | CEDARS-SINAI MEDICAL CENTER (US) | 2013-01-31 | — | — | WO | disclosed |