Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.82 |
| ▸ | ERBB2 | P04626 | 10/20 | 0.82 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.82 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.82 |
| ▸ | ABL1 | P00519 | 1/20 | 0.82 |
| ▸ | SRC | P12931 | 1/20 | 0.82 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.82 |
| ▸ | FLT3 | P36888 | 1/20 | 0.82 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.73 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15876899 | 0.90 | EGFR (1.00) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL15876902 | 0.90 | EGFR (1.00) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL15876900 | 0.90 | EGFR (1.00) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL14671647 | 0.88 | EGFR (0.77) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL14671617 | 0.88 | EGFR (0.71) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL15877088 | 0.87 | EGFR (0.85) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL15877086 | 0.87 | EGFR (0.85) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL14671641 | 0.86 | EGFR (0.86) | EGFRERBB2ERBB4ABL1SRC | |
| SCHEMBL15877129 | 0.86 | EGFR (0.83) | EGFRERBB2ERBB4PDGFRBABL1 | |
| SCHEMBL15877080 | 0.86 | EGFR (0.81) | EGFRERBB2ERBB4PDGFRBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013013640-A1 | QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION AND APPLICATION THEREOF | 上海医药集团股份有限公司 (CN) | 2013-01-31 | — | — | WO | disclosed |