SCHEMBL14671815

SCHEMBL14671815

Cc1ccc2c(c1)C(c1ccccc1)(c1ccc(N(c3ccccc3)c3ccccc3)cc1)c1cc(C)c3ccccc3c1-2

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14671794 0.99 PDK2 (0.32) PDK2
SCHEMBL20755378 0.93
SCHEMBL14671821 0.92 PDK2 (0.33) PDK2
SCHEMBL15682248 0.91
SCHEMBL15828176 0.89
SCHEMBL14671757 0.89
SCHEMBL15828132 0.87 CYP1A2 (0.33)
SCHEMBL14671819 0.86 CYP1A2 (0.34)
SCHEMBL15828157 0.85
SCHEMBL15828192 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9178159-B2 Copolymers with functionalized side chains MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
US-9178159-B2 Copolymers with functionalized side chains MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
US-20140175420-A1 COPOLYMERS WITH FUNCTIONALIZED SIDE CHAINS MERCK PATENT GMBH (DE) 2014-06-26 US disclosed
US-20140175420-A1 COPOLYMERS WITH FUNCTIONALIZED SIDE CHAINS MERCK PATENT GMBH (DE) 2014-06-26 US disclosed
WO-2013013754-A1 COPOLYMERS WITH FUNCTIONALIZED SIDE CHAINS MERCK PATENT GMBH (DE) 2013-01-31 WO disclosed