SCHEMBL14673245

SCHEMBL14673245

CCCCCCCCCCCCOc1cc2c3ccsc3c(OCCCCCCCCCCCC)cc2c2ccsc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.38
MEN1 O00255 1/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38
ADRA2A P08913 1/20 0.38
MAPT P10636 1/20 0.38
OPRK1 P41145 1/20 0.38
HTR2B P41595 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
CHUK O15111 1/20 0.38
DAPK3 O43293 1/20 0.38
JAK2 O60674 1/20 0.38
ROCK2 O75116 1/20 0.38
PRKCG P05129 1/20 0.38
CDK1 P06493 1/20 0.38
PIM1 P11309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3167254 0.85 PPARG (0.41) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL14673706 0.82 PRSS1 (0.33) LMNAALDH1A1
SCHEMBL12918761 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL8974623 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL31071684 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL6743869 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL8974064 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL202536 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL20678395 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL8975367 0.78 NR5A1 (0.45) TLR8MEN1NR1I2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035004-B2 Semiconducting compounds and devices incorporating same POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-9035004-B2 Semiconducting compounds and devices incorporating same POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-9035004-B2 Semiconducting compounds and devices incorporating same POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20130035464-A1 Semiconducting Compounds and Devices Incorporating Same USINVEST LLC 2013-02-07 US disclosed
US-20130035464-A1 Semiconducting Compounds and Devices Incorporating Same USINVEST LLC 2013-02-07 US disclosed