Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.47 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL14676212 | 1.00 | KDM4E (0.49) | KDM4ENPC1LMNAHTTRAB9A | |
| SCHEMBL5283301 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5287933 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5285277 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5301618 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5810521 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5297432 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5816934 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5295539 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA | |
| SCHEMBL5290628 | 0.98 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663386-B2 | Extraction of noble metal (ions) by means of ionic liquids | TECHNISCHE UNIVERSITAT DRESDEN (DE) | 2017-05-30 | — | — | US | disclosed |
| EP-2739572-B1 | EXTRACTION OF METAL (IONS) BY MEANS OF IONIC LIQUIDS | UNIV DRESDEN TECH (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-20140246370-A1 | EXTRACTION OF NOBLE METAL (IONS) BY MEANS OF IONIC LIQUIDS | HELMHOLTZ-ZENTRUM DRESDEN - ROSSENDORF E.V. (DE) | 2014-09-04 | — | — | US | disclosed |
| EP-2739572-A1 | EXTRACTION OF NOBLE METAL (IONS) BY MEANS OF IONIC LIQUIDS | Technische Universität Dresden (DE) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013017588-A1 | EXTRACTION OF NOBLE METAL (IONS) BY MEANS OF IONIC LIQUIDS | Technische Universität Dresden (DE) | 2013-02-07 | — | — | WO | disclosed |