Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690876 | 0.74 | CYP1A2 (0.48) | CYP1A2PKMPTK2BL3MBTL1ALDH1A1 | |
| SCHEMBL30590684 | 0.70 | — | — | |
| SCHEMBL26112743 | 0.70 | TDP1 (0.40) | — | |
| SCHEMBL12572603 | 0.69 | CYP1A2 (0.44) | CYP1A2PKMPTK2BL3MBTL1ALDH1A1 | |
| SCHEMBL17147382 | 0.69 | — | — | |
| SCHEMBL3483750 | 0.69 | — | — | |
| SCHEMBL1138743 | 0.67 | EPHX1 (0.44) | CYP1A2PKMPTK2BL3MBTL1ALDH1A1 | |
| SCHEMBL22454078 | 0.67 | CYP1A2 (0.43) | CYP1A2PKMPTK2BL3MBTL1ALDH1A1 | |
| SCHEMBL3648521 | 0.65 | CRBN (0.48) | CYP1A2PKMPTK2BL3MBTL1ALDH1A1 | |
| SCHEMBL31066656 | 0.65 | CYP1A2 (0.41) | CYP1A2PKMPTK2BL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |