Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177806 | 0.98 | HPGD (0.69) | HPGDMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL14679436 | 0.95 | HPGD (0.73) | HPGDMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL14679435 | 0.88 | HPGD (0.68) | HPGDMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL21391252 | 0.88 | HPGD (0.83) | HPGDMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10170678 | 0.83 | HPGD (1.00) | HPGDMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL11966138 | 0.83 | HPGD (0.55) | HPGDMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL29023569 | 0.83 | HDAC3 (0.56) | HPGDL3MBTL1KMT2ALMNAPOLB | |
| SCHEMBL19102882 | 0.82 | HPGD (0.59) | HPGDL3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL14817909 | 0.82 | HPGD (0.73) | HPGDMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL14679158 | 0.82 | NPC1 (0.53) | HPGDL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367668-B2 | Pyridazinone derivatives | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-02-05 | — | — | US | disclosed |