SCHEMBL14682199

SCHEMBL14682199

COc1ccc(-c2ccc(Oc3cccc(Oc4ccc(-c5ccc(OC(=O)Oc6ccc(C(C)(C)c7ccc(OC(C)=O)cc7)cc6)c(C)c5)cc4)c3)cc2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ACACB O00763 3/20 0.41
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 3/20 0.39
GAA P10253 1/20 0.39
MTNR1B P49286 2/20 0.38
MTNR1A P48039 1/20 0.38
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
ACACA Q13085 2/20 0.38
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
POLB P06746 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14682201 0.94 ACACB (0.42) MEN1KMT2AACACBMAPTTDP1
SCHEMBL4402851 0.93 ACACB (0.43) MEN1KMT2AACACBMTNR1BMTNR1A
SCHEMBL14682195 0.92 KMT2A (0.43) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL14682196 0.91 KMT2A (0.42) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL4403576 0.89 ACACB (0.45) ACACBMTNR1BMTNR1APPARGPPARD
SCHEMBL15417114 0.89 KMT2A (0.42) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL13144084 0.88 KMT2A (0.43) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL14682210 0.87 ACACB (0.40) MEN1KMT2AACACBMAPTTDP1
SCHEMBL14682215 0.86 ACACB (0.39) MEN1KMT2AACACBMAPTTDP1
SCHEMBL18712961 0.85 ACACB (0.47) MEN1KMT2AACACBMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9618881-B2 Biaryl polycarbonate intermediate transfer members XEROX CORPORATION (US) 2017-04-11 US disclosed
US-20140079446-A1 BIARYL POLYCARBONATE INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2014-03-20 US disclosed
US-20130034733-A1 BIARYL POLYCARBONATE INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2013-02-07 US disclosed