Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14684357 | 0.90 | SMPD1 (0.48) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL14684418 | 0.86 | SMPD1 (0.46) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| Iowh-032 SCHEMBL1114552 | 0.85 | SMPD1 (0.51) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL14684358 | 0.84 | KMT2A (0.45) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL16727928 | 0.84 | KMT2A (0.52) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL14684460 | 0.82 | SMPD1 (0.47) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL14684360 | 0.81 | SMPD1 (0.47) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL18286123 | 0.80 | SMPD1 (0.58) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL1114330 | 0.79 | KMT2A (0.51) | SMPD1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL31591596 | 0.77 | KMT2A (0.52) | SMPD1KMT2APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013019169-A1 | PHOSPHATE PRODRUGS | INSTITUTE FOR ONEWORLD HEALTH (US) | 2013-02-07 | — | — | WO | disclosed |