Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14684375 | 0.84 | PDE4B (0.52) | PDE4BPDE4DPDE4A | |
| SCHEMBL4123097 | 0.83 | PDE4B (0.70) | PDE4BPDE4DPDE4A | |
| SCHEMBL14684444 | 0.83 | PDE4B (0.49) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL4115895 | 0.83 | PDE4B (0.73) | PDE4BPDE4D | |
| SCHEMBL4121765 | 0.82 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL14684443 | 0.80 | PDE4B (0.51) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL14684520 | 0.79 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL14684379 | 0.78 | PDE4B (0.51) | PDE4BPDE4DPDE4A | |
| SCHEMBL14684431 | 0.77 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL14684511 | 0.73 | PDE4B (0.44) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013018374-A1 | KETONE DERIVATIVE AND DRUG CONTAINING SAME | 杏林製薬株式会社 (JP) | 2013-02-07 | — | — | WO | disclosed |