SCHEMBL14686199

SCHEMBL14686199

COc1ccc(C2Oc3cc(O)cc(O)c3CC2O)cc1OC1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 0.53
KDM4E B2RXH2 5/20 0.53
PTGS1 P23219 5/20 0.53
GAA P10253 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HSD17B10 Q99714 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
APEX1 P27695 3/20 0.53
RECQL P46063 3/20 0.53
SNCA P37840 3/20 0.53
PKM P14618 2/20 0.53
ALPL P05186 2/20 0.53
POLB P06746 2/20 0.53
CYP3A4 P08684 2/20 0.53
PTGS2 P35354 2/20 0.53
RAD52 P43351 2/20 0.53
HPGD P15428 2/20 0.53
ALOX15 P16050 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25390204 1.00 BACE1 (0.53) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL14686056 1.00 BACE1 (0.53) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL14686099 0.97 BACE1 (0.53) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL14700129 0.92 BACE1 (0.57) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL14700137 0.91 BACE1 (0.59) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL17534890 0.91 BACE1 (0.59) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL17548765 0.91 BACE1 (0.59) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL350730 0.90 KDM1A (0.51) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL30646900 0.89 BACE1 (0.50) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL30217588 0.89 PTGS1 (0.64) BACE1KDM4EPTGS1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140171631-A1 SYNTHESIS OF CATECHIN AND EPICATECHIN CONJUGATES NESTEC S.A. (CH) 2014-06-19 US claimed
EP-2557079-A1 Synthesis of catechin and epicatechin conjugates Nestec S.A. (CH) 2013-02-13 EP claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US disclosed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US disclosed
US-20240355451-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY NESTLE SA (CH) 2024-10-24 US disclosed
EP-4391834-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY Société des Produits Nestlé S.A. (CH) 2024-07-03 EP disclosed
US-20240101791-A1 POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-03-28 US disclosed
WO-2024059282-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-03-21 WO disclosed
US-20230255989-A1 GLYCAN COMPOSITIONS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-08-17 US disclosed
WO-2023025722-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY Société des Produits Nestlé S.A. (CH) 2023-03-02 WO disclosed
US-20210137956-A1 GLYCAN COMPOSITIONS AND USES THEREOF HERCULES CAPITAL, INC. 2021-05-13 US disclosed
US-9901595-B2 Glycan therapeutics for reducing blood ammonia KALEIDO BIOSCIENCES, INC. (US) 2018-02-27 US disclosed
US-9757403-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2017-09-12 US disclosed
US-20170246201-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2017-08-31 US disclosed
US-20170151268-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2017-06-01 US disclosed
US-20170151269-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2017-06-01 US disclosed
US-9492473-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2016-11-15 US disclosed
US-20160213702-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2016-07-28 US disclosed
US-20140171631-A1 SYNTHESIS OF CATECHIN AND EPICATECHIN CONJUGATES NESTEC S.A. (CH) 2014-06-19 US disclosed
EP-2557079-A1 Synthesis of catechin and epicatechin conjugates Nestec S.A. (CH) 2013-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171631-A1 SYNTHESIS OF CATECHIN AND EPICATECHIN CONJUGATES COMT, NQO1, UGT1A1 BACE1 4116/4885KDM4E 770/4885PTGS1 743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.