Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3047996 | 0.99 | PTGDR2 (0.42) | PTGDR2MEN1KMT2APOLBCNR1 | |
| SCHEMBL3273942 | 0.96 | PTGDR2 (0.46) | PTGDR2KMT2APOLBCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL3288810 | 0.96 | PTGDR2 (0.45) | PTGDR2KMT2APOLBCNR1CNR2 | |
| SCHEMBL15103816 | 0.93 | GAA (0.45) | PTGDR2KMT2ACNR1CNR2CACNA1H | |
| Hydrochloric Acid SCHEMBL3273505 | 0.92 | GAA (0.44) | PTGDR2KMT2ACNR1CNR2CACNA1H | |
| SCHEMBL15103767 | 0.88 | HSD17B10 (0.50) | PTGDR2KMT2ACNR1CNR2CACNA1H | |
| SCHEMBL15103796 | 0.87 | GAA (0.51) | PTGDR2MEN1KMT2ACNR1CNR2 | |
| SCHEMBL15103733 | 0.87 | GAA (0.51) | PTGDR2MEN1KMT2ACNR1CNR2 | |
| SCHEMBL15103780 | 0.87 | GAA (0.51) | PTGDR2MEN1KMT2ACNR1CNR2 | |
| Hydrochloric Acid SCHEMBL3281099 | 0.87 | PREP (0.43) | KMT2ACACNA1HCACNA1BTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057116-B1 | NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-02-13 | — | — | EP | claimed |