Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14693148 | 0.93 | KDR (0.54) | KDRBRAF | |
| SCHEMBL14437841 | 0.92 | KDR (0.46) | KDRBRAF | |
| SCHEMBL14693158 | 0.89 | KDR (0.43) | KDRBRAF | |
| SCHEMBL14693143 | 0.89 | KDR (0.47) | KDRBRAF | |
| SCHEMBL12673833 | 0.89 | KDR (0.64) | KDRBRAF | |
| SCHEMBL1895479 | 0.88 | KDR (0.56) | KDRBRAF | |
| SCHEMBL14437328 | 0.84 | PTPN2 (0.46) | KDRBRAF | |
| SCHEMBL12503696 | 0.82 | KDR (0.57) | KDRBRAF | |
| SCHEMBL12673779 | 0.81 | KDR (0.65) | KDRBRAF | |
| SCHEMBL1893099 | 0.81 | KDR (0.48) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372981-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |