Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12832288 | 0.94 | MEN1 (0.55) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL17814732 | 0.85 | MEN1 (0.49) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL1083748 | 0.84 | MEN1 (0.74) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL18465895 | 0.83 | MEN1 (0.45) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL14338738 | 0.80 | MEN1 (0.57) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL5712581 | 0.78 | MEN1 (0.77) | MEN1KMT2AUSP2POLBPPARG | |
| Water SCHEMBL185914 | 0.77 | MEN1 (0.76) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL17267894 | 0.77 | MEN1 (0.76) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL17265451 | 0.77 | MEN1 (0.66) | MEN1KMT2AUSP2POLBPPARG | |
| SCHEMBL29569925 | 0.77 | MEN1 (0.79) | MEN1KMT2AUSP2POLBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372868-B2 | Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging | VANDERBILT UNIVERSITY (US) | 2013-02-12 | — | — | US | disclosed |