Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258695 | 1.00 | KDM1A (0.44) | KDM1ATLR4TYMPHDAC4HDAC2 | |
| SCHEMBL3534201 | 0.87 | KDM1A (0.38) | KDM1ATLR4TYMP | |
| SCHEMBL130772 | 0.82 | TLR4 (0.56) | KDM1ATLR4TYMPMAPT | |
| SCHEMBL30130600 | 0.78 | TLR4 (0.56) | KDM1ATLR4MAPT | |
| SCHEMBL1964176 | 0.75 | TLR4 (0.48) | KDM1ATLR4MAPT | |
| SCHEMBL11443954 | 0.75 | TLR4 (0.58) | KDM1ATLR4MAPT | |
| SCHEMBL13576613 | 0.73 | KDM1A (0.42) | KDM1ATLR4 | |
| SCHEMBL9593863 | 0.73 | KDM1A (0.36) | KDM1ATLR4 | |
| SCHEMBL10258708 | 0.73 | KDM1A (0.36) | KDM1ATLR4 | |
| SCHEMBL5175094 | 0.72 | TLR4 (0.50) | KDM1ATLR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234949-B1 | METHOD FOR THE PRODUCTION OF 4,4'-[1-(TRIFLUOROMETHYL)ALKYLIDENE]-BIS-(2,6-DIPHENYLPHENOLS) | BASF SE (DE) | 2013-02-20 | — | — | EP | disclosed |