Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14695862 | 1.00 | AR (0.56) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14696192 | 1.00 | AR (0.56) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14694904 | 0.90 | AR (0.71) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14694978 | 0.90 | AR (0.71) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14695495 | 0.90 | AR (0.71) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14707387 | 0.85 | AR (0.42) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14695730 | 0.83 | AR (0.57) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14695277 | 0.83 | AR (0.57) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14695268 | 0.83 | AR (0.57) | ARHTTHIF1ACACNA1GMAPT | |
| SCHEMBL14695096 | 0.83 | AR (0.57) | ARHTTHIF1ACACNA1GMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744773-B1 | FLUORINATED BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY (CA) | 2016-11-02 | — | — | EP | disclosed |
| EP-2744773-B1 | FLUORINATED BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY (CA) | 2016-11-02 | — | — | EP | disclosed |
| WO-2013028572-A1 | FLUORINATED BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2013-02-28 | — | — | WO | disclosed |
| US-20130045204-A1 | FLUORINATED BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20130045204-A1 | FLUORINATED BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20130045204-A1 | FLUORINATED BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045204-A1 | FLUORINATED BISPHENOL ETHER COMPOUNDS AND METHODS FOR THEIR USE | AR, ESRRA, ESR1 | AR 1/4885HTT 3985/4885HIF1A 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.