Arildone

Arildone

SCHEMBL146967

CCC(=O)C(CCCCCCOc1ccc(OC)cc1Cl)C(=O)CC

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.47
CYSLTR2 Q9NS75 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43
PPARA Q07869 5/20 0.43
S1PR4 O95977 1/20 0.43
MAPT P10636 6/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 2/20 0.43
TSHR P16473 1/20 0.43
HPGD P15428 1/20 0.41
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 1/20 0.41
PPARD Q03181 3/20 0.41
PPARG P37231 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arildone SCHEMBL29807845 1.00 MRGPRX4 (0.47) MRGPRX4CYSLTR2CYSLTR1PPARAS1PR4
SCHEMBL11309550 1.00 MRGPRX4 (0.47) MRGPRX4CYSLTR2CYSLTR1PPARAS1PR4
SCHEMBL11546537 1.00 MRGPRX4 (0.47) MRGPRX4CYSLTR2CYSLTR1PPARAS1PR4
SCHEMBL11308216 0.99 MRGPRX4 (0.48) MRGPRX4CYSLTR2CYSLTR1PPARAS1PR4
SCHEMBL11359845 0.95 MRGPRX4 (0.46) MRGPRX4CYSLTR2CYSLTR1PPARAS1PR4
Arildone SCHEMBL28264892 0.94 MRGPRX4 (0.43) MRGPRX4CYSLTR2CYSLTR1PPARAS1PR4
SCHEMBL11614513 0.93 PPARA (0.44) PPARAMAPTL3MBTL1TDP1ALDH1A1
SCHEMBL11544717 0.88 PPARA (0.42) PPARAMAPTL3MBTL1TDP1ALDH1A1
SCHEMBL11455904 0.88 NPC1 (0.43) PPARAMAPTL3MBTL1TDP1ALDH1A1
SCHEMBL11319008 0.88 MRGPRX4 (0.49) MRGPRX4CYSLTR2CYSLTR1PPARAS1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO claimed
WO-2024215771-A1 SUBSTITUTED PHENYL ETHYNYL PYRIMIDINES AS POTENT INHIBITORS OF ALPHAVIRUSES SOUTHERN RESEARCH INSTITUTE (US) 2024-10-17 WO claimed
EP-4262812-A1 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS Southern Research Institute (US) 2023-10-25 EP claimed
WO-2023122212-A2 SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SOUTHERN RESEARCH INSTITUTE (US) 2023-06-29 WO claimed
EP-4125845-A1 NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES Southern Research Institute (US) 2023-02-08 EP claimed
US-11534375-B2 Solvent-free method of encapsulating a hydrophobic active AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-12-27 US claimed
EP-4021413-A1 LIPOSOMAL TROPONOID COMPOUND FORMULATIONS United States Government as Represented by The Department of Veterans Affairs (US) 2022-07-06 EP claimed
WO-2022133323-A1 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS SOUTHERN RESEARCH INSTITUTE (US) 2022-06-23 WO claimed
WO-2021203048-A1 NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES SOUTHERN RESEARCH INSTITUTE (US) 2021-10-07 WO claimed
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES Spectral Analytics, Inc. (US) 2021-09-30 US claimed
EP-1098641-A4 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA ST JUDE PHARMACEUTICALS INC (US) 2003-08-27 EP claimed
US-6576636-B2 Treating a noncentral nervous system by administering a covalent conjugate of a C8-26, unbranched, naturally occurring fatty acid and a drug, provided the drug is not an adenosine receptor agonist/antagonist; anticarcinogenics PROTARGA, INC. 2003-06-10 US claimed
WO-2003030934-A2 CPG FORMULATIONS AND RELATED METHODS MERIAL LIMITED (US) 2003-04-17 WO claimed
US-6548055-B1 Activation cell in immunology system THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2003-04-15 US claimed
EP-0776659-B1 Delivery device for medicaments by the intravaginal route AVENTIS PHARMA SA (FR) 2002-04-10 EP claimed
WO-2001097749-A2 THE USE OF SYNTHETIC, NON-HORMONAL 21-AMINOSTEROIDS AND THEREOF KOTZE, GAVIN, SALOMON (ZA) 2001-12-27 WO claimed
EP-1098641-A1 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA Texas Pharmaceuticals, Inc. (US) 2001-05-16 EP claimed
WO-2000006143-A1 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA TEXAS PHARMACEUTICALS, INC. (US) 2000-02-10 WO claimed
US-5788980-A CONTAINING POLYSILOXANE RING MATRIX AND FATTY ESTER; CONTRACEPTIVE ROUSSEL UCLAF (FR) 1998-08-04 US claimed
WO-1998017282-A1 METHODS OF USING SUCROSE OCTASULFATE TO TREAT OR PREVENT ENVELOPED VIRUS INFECTION VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-04-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES NCOA1, NCOA2, NCOA3 MRGPRX4 906/4885CYSLTR2 673/4885CYSLTR1 677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.