Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14697177 | 0.93 | MAPT (0.78) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697174 | 0.88 | MAPT (0.77) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697281 | 0.85 | KMT2A (1.00) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697292 | 0.85 | MAPT (0.74) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697132 | 0.84 | MAPT (0.81) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697267 | 0.84 | MAPT (0.81) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697311 | 0.84 | MAPT (0.75) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697310 | 0.83 | MAPT (0.80) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697084 | 0.83 | MAPT (0.80) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL14697159 | 0.83 | MAPT (0.72) | MAPTKMT2ASMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744787-B1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | SOUTHERN RES INST (US) | 2016-11-02 | — | — | EP | disclosed |
| EP-2744787-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | Southern Research Institute (US) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013025508-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | SOUTHERN RESEARCH INSTITUTE (US) | 2013-02-21 | — | — | WO | disclosed |