SCHEMBL146975

SCHEMBL146975

Fc1[c]c(Cl)cc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260879 0.85
SCHEMBL57470 0.78
SCHEMBL261753 0.78
SCHEMBL28771110 0.76 CA12 (0.35)
SCHEMBL17514866 0.75
SCHEMBL5730320 0.74
SCHEMBL2344125 0.74
SCHEMBL1401619 0.74
SCHEMBL2353732 0.74
SCHEMBL1116593 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024145505-A1 PYRIMIDINE CARBOXAMIDE COMPOUNDS ACRIVON THERAPEUTICS, INC. (US) 2024-07-04 WO claimed
EP-3807266-A1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS Janssen Pharmaceutica N.V. (BE) 2021-04-21 EP claimed
CN-112585128-A Pyrazole derivatives as MALT1 inhibitors 詹森药业有限公司 2021-03-30 CN claimed
WO-2019243964-A1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2019-12-26 WO claimed
US-20180110223-A1 PHENOXY- OR PYRIDIN-2-YLOXY-AMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2018-04-26 US claimed
EP-3286170-A1 PHENOXY- OR PYRIDIN-2-YLOXY-AMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2018-02-28 EP claimed
WO-2016201052-A1 BRIDGED BICYCLIC KALLIKREIN INHIBITORS GLOBAL BLOOD THERAPEUTICS, INC. (US) 2016-12-15 WO claimed
US-20160362427-A1 BRIDGED BICYCLIC KALLIKREIN INHIBITORS GLOBAL BLOOD THERAPEUTICS, INC. 2016-12-15 US claimed
WO-2016169831-A1 PHENOXY- OR PYRIDIN-2-YLOXY-AMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2016-10-27 WO claimed
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP claimed
US-20080108663-A1 Cyclopropyl Piperidine Glycine Transporter Inhibitors MERCK SHARP & DOHME LLC 2008-05-08 US claimed
JP-2008514705-A 2008-05-08 JP claimed
WO-2008009908-A1 PYRIDO [2, 3-B] PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2008-01-24 WO claimed
EP-1797035-A2 CYCLOPROPYL PIPERIDINE GLYCINE TRANSPORTER INHIBITORS Merck & Co., Inc. (US) 2007-06-20 EP claimed
EP-1431299-B1 IMIDAZO(1,2-a)PYRIMIDINES AND FUNGICIDE COMPOSITIONS CONTAINING THE SAME SUMITOMO CHEMICAL CO (JP) 2007-05-23 EP claimed
US-7211545-B2 Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-01 US claimed
US-7186831-B2 5-halo-2-alkyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines BAYER CROPSCIENCE LP (DE) 2007-03-06 US claimed
WO-2006039221-A2 CYCLOPROPYL PIPERIDINE GLYCINE TRANSPORTER INHIBITORS MERCK & CO., INC. (US) 2006-04-13 WO claimed
US-20040235865-A1 Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-25 US claimed
EP-1431299-A1 IMIDAZO(1,2-a)PYRIMIDINES AND FUNGICIDE COMPOSITIONS CONTAINING THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-23 EP claimed