SCHEMBL14699595

SCHEMBL14699595

CCC(C)(C)CC(C(=O)OCCc1ccc(OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)F)cc1)C(C)(CC)CC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
PPARA Q07869 8/20 0.32
PPARG P37231 7/20 0.32
PPARD Q03181 4/20 0.32
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13800884 0.83 CA1 (0.36) CA1CA2PPARAPPARGPPARD
SCHEMBL13024735 0.81 CA1 (0.41) CA1CA2PPARAPPARGPPARD
SCHEMBL13024729 0.80 CA1 (0.36) CA1CA2PPARAPPARGPPARD
SCHEMBL14699600 0.79 CA1 (0.35) CA1CA2PPARAPPARGPPARD
SCHEMBL14699605 0.78
SCHEMBL13024734 0.76 CA1 (0.47) CA1CA2PPARAPPARGPPARD
SCHEMBL13125198 0.76 CA1 (0.47) CA1CA2PPARAPPARGPPARD
SCHEMBL13024739 0.76 CA1 (0.47) CA1CA2PPARAPPARGPPARD
SCHEMBL13823127 0.76 CA1 (0.39) CA1CA2PPARAPPARGPPARD
SCHEMBL13024859 0.75 POLB (0.38) CA1CA2PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2071404-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC DEVICE CANON KK (JP) 2013-02-13 EP disclosed