Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCE | Q02156 | 2/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14700123 | 0.94 | PRKCE (0.43) | PRKCEPRKCQPRKCDNFE2L2TTR | |
| SCHEMBL8247911 | 0.90 | POLB (0.45) | PRKCEPRKCQPRKCDMAPTAPP | |
| SCHEMBL14700118 | 0.87 | APP (0.40) | PRKCEPRKCQPRKCDALOX5MAPT | |
| SCHEMBL14686039 | 0.81 | GSK3B (0.57) | TTRALOX5MAPTAPPHPGD | |
| SCHEMBL14686038 | 0.81 | GSK3B (0.57) | TTRALOX5MAPTAPPHPGD | |
| SCHEMBL30383259 | 0.78 | KDM4E (0.70) | HTR1AMAPTAPPHPGDKDM4E | |
| SCHEMBL13183882 | 0.78 | KDM4E (0.70) | HTR1AMAPTAPPHPGDKDM4E | |
| SCHEMBL25203862 | 0.77 | CYP1A1 (0.47) | NFE2L2TTRMAPTAPPHPGD | |
| SCHEMBL30382912 | 0.77 | CYP1A1 (0.47) | NFE2L2TTRMAPTAPPHPGD | |
| SCHEMBL25759920 | 0.76 | MAOB (0.50) | PRKCEPRKCQPRKCDNFE2L2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2557079-A1 | Synthesis of catechin and epicatechin conjugates | Nestec S.A. (CH) | 2013-02-13 | — | — | EP | disclosed |