Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.63 |
| ▸ | HTR2B | P41595 | 17/20 | 0.63 |
| ▸ | HTR2A | P28223 | 16/20 | 0.63 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843808 | 0.83 | HTR2C (0.46) | HTR2CHTR2BHTR2ACHEK1CCNA2 | |
| SCHEMBL2574952 | 0.82 | HTR2C (0.63) | HTR2CHTR2BHTR2A | |
| SCHEMBL10216948 | 0.78 | HTR2C (0.87) | HTR2CHTR2BHTR2A | |
| SCHEMBL10217159 | 0.77 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL10217173 | 0.77 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL2573130 | 0.77 | HTR2C (0.61) | HTR2CHTR2BHTR2ACHEK1CCNA2 | |
| SCHEMBL2573131 | 0.76 | HTR2C (0.56) | HTR2CHTR2BHTR2A | |
| SCHEMBL10217162 | 0.76 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL10217177 | 0.76 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL9948356 | 0.76 | HTR2C (0.83) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384328-B1 | 6,7,8,9-TETRAHYDRO-5H-1,4,7,10A-TETRAAZA-CYCLOHEPT[F]INDENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR PREPARING THEM | BOEHRINGER INGELHEIM INT (DE) | 2013-02-13 | — | — | EP | disclosed |