⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628037 | 0.69 | — | — | |
| SCHEMBL16939953 | 0.69 | — | — | |
| SCHEMBL24014599 | 0.69 | — | — | |
| SCHEMBL20898688 | 0.68 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL23523345 | 0.68 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL23523344 | 0.68 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL21241607 | 0.67 | — | — | |
| SCHEMBL13236612 | 0.65 | — | — | |
| SCHEMBL16708769 | 0.64 | — | — | |
| SCHEMBL1938746 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989196-B1 | PIPERIDINOYLPYRROLIDINES AS MELANOCORTIN TYPE 4 RECEPTOR AGONISTS | PFIZER LTD (GB) | 2013-02-13 | — | — | EP | disclosed |