Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521690 | 0.91 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL25501979 | 0.86 | HDAC1 (0.43) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14703494 | 0.80 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14703491 | 0.79 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14703488 | 0.78 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL23080794 | 0.78 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| Hydrochloric Acid SCHEMBL23270114 | 0.77 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14703486 | 0.75 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14703492 | 0.75 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL840657 | 0.75 | HDAC1 (0.62) | HDAC3HDAC1HDAC2HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040924-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR THE INHIBITION AND AMELIORATION OF DISEASE | ALLACCEM, INC. (US) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040924-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR THE INHIBITION AND AMELIORATION OF DISEASE | PKD1, VHL, PKD2 | HDAC3 2094/4885HDAC1 448/4885HDAC2 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.